Destructible cryogenic labels for tubes, cryo vials and other containers. They have been designed to securely seal samples and products that require prior authorization to be accessed. Once applied, these destructible labels cannot be removed without being destroyed, ideal for pharmaceutical and biomedical research laboratories, IVF clinics, cell banks and tissue banks, bio-repositories and any industry that handles sensitive or hazardous material. They are made with an extra-permanent adhesive, specifically designed for extreme low-temperature storage, to ensure they retain adhesion, integrity and print. Any attempt to open or access the content will destroy the seal, indicating that the sample or product has been tampered with, and thus has been compromised.